The stimulating effect of coffee goes beyond caffeine
Megan Brooks: New research suggests there may be other underlying mechanisms that explain this effect. “There is a widespread expectation that coffee increases alertness and psychomotor performance. By gaining a deeper understanding of the mechanisms underlying this biological phenomenon, we pave the way to investigate the factors that may…”
8 foods and drinks that irritate your bladder
Some foods and drinks can trigger a sudden trip to the bathroom. By Anne Harding. Eating or drinking certain things can irritate your bladder, and this can be the case even if you don't have an overactive bladder. Basically, your bladder is sensitive to irritants that can trigger the urge to go. Pay attention to these…
Cardiovascular safety of testosterone replacement therapy
A randomized, controlled clinical trial, recently published in The New England Journal of Medicine (NEJM), evaluated the cardiovascular safety of testosterone replacement therapy in middle-aged and older men with hypogonadism. The trial included 5,246 men aged 45 to 80 years with high risk or pre-existing cardiovascular disease, symptoms of…
PAHO and Venezuela agree to acquire HPV and pneumococcal vaccines
By EFE. At the end of 2022, the government announced that it would begin administering the human papillomavirus (HPV) vaccine in the second quarter of 2023, but it has not explained when these doses will begin to be administered or how many have been acquired. The Venezuelan government announced this Monday the strengthening of its immunization system through new…
Low-dose amoxicillin monotherapy is highly effective against syphilis in people with HIV
By Miguel Vasquez. This treatment may be an alternative to intramuscular penicillin G injection, with fewer side effects, although further studies are needed. Both monotherapy with low doses of amoxicillin and the use of higher doses of this antibiotic in combination with probenecid have shown high efficacy in…
Real-world data confirm the effectiveness of dolutegravir-based dual therapy
By Zekerie Redzheb. More than six years of real-world data collected from people with HIV who switched to two-drug regimens based on dolutegravir confirm comparable efficacy to three-drug regimens, aligning with previous clinical trial findings. Dr. Conor Bowman and colleagues at the Royal Free Hospital…
How the I=I movement changed sex for everyone
Reflecting on seven years of undetectable equals untransmittable. By Desirée Guerrero. Although it may still seem like a relatively new concept to many, the U=U (U=U) movement has evolved alongside the HIV epidemic for decades. “Undetectable equals untransmittable,” more popularly known as U=U, is the globally accepted scientific consensus that continues to change…
New studies reinforce the long-term efficacy and safety profile of combination therapy with an integrase inhibitor.
By John Parkinson. Five-year pooled data from two Phase 3 studies analyzed 50 mg/emtricitabine 200 mg/tenofovir alafenamide 25 mg tablets, B/F/TAF. Two Phase 3 studies provide long-term data demonstrating the sustained efficacy and clinical safety of B/F/TAF. Specifically, the Week 240 results reinforce the role…
PEP prevents HIV within 72 hours of unexpected exposure, but few people talk about it.
By Michael Chancley Jr., MSW. During my time as a PrEP navigator, I received calls almost every week from people who were frantic about possibly having been exposed to HIV. The scenario played out in many different ways, but almost always included one common trait: none of the callers knew that post-exposure prophylaxis is not…
Why is May 17th the International Day Against Homophobia, Transphobia and Biphobia?
Thousands of initiatives in more than 130 countries, including 37 where same-sex relations are illegal. Since 2005, May 17th has been celebrated as the International Day Against Homophobia, Transphobia and Biphobia, commemorating the removal of homosexuality from the World Health Organization's list of mental illnesses.
The WHO declares the end of the global health emergency Mpox
The World Health Organization (WHO) has ended the global health emergency for COVID-19, marking the end of a 10-month juggling act by the UN health agency as it struggled to cope with concurrent global pandemics. The announcement comes just days after…
A potential biomarker indicates in which people HIV therapy could be discontinued
People who contract HIV must follow a lifelong course of antiretroviral drugs to keep the infection under control and prevent transmission to others. However, in some patients, the virus does not reappear when treatment is stopped. These minority cases are known among researchers in the field as post-treatment controllers, and their…
Now that the public health emergency is coming to an end, how do we feel about it?
By Paul Sax As you no doubt heard, on Friday, May 5, 2023, the WHO declared the end of the global health emergency for COVID-19. Here in the U.S., the federal public health emergency will expire on May 11. That's a Thursday, in just a few days. These events reflect two realities that, while seemingly contradictory, make…
Recreational cannabis use is negative for the mental health of adolescents
By Elizabeth Short, Staff Writer, MedPage Today. National data shows that cannabis use that doesn't reach the level of a diagnosable substance use disorder was associated with negative mental health effects. In the 2015-2019 National Surveys on Drug Use and Health, 2.5% of participants…
The WHO declares the end of the international emergency for COVID-19
By Pablo Linde – El País, Madrid. In these more than three years, 765 million diagnoses and 6.9 million deaths have been officially recorded, figures that fall far short, according to all estimates. COVID-19 is no longer an international health emergency. 1,191 days (three years and three months) have passed since…
WHO experts weigh whether the world is ready to end the COVID-19 emergency
By Reuters: World Health Organization experts meet Thursday to decide whether COVID-19 remains an emergency. A panel of global health experts will meet Thursday to decide whether COVID-19 remains an emergency under the rules of the World Health Organization, a status that helps…
